Regression Analysis using ACS 5 year estimates

Hello!

I am grad student at NC State working with a fellow student on a project involving ArcGIS and ACS 5-year estimate data. We would like to construct a model using ordinary least squares (and eventually geographically weighted regression) with various ACS variables as independent variables. I am unsure how to incorporate the MOEs included in ACS data into these models.

Any help for a newbie at using survey data to construct models accurately (particularly in ArcGIS) is much appreciated!

Thanks,

Jacob